Cytokines and Signaling Molecules Predict Clinical Outcomes in Sepsis
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چکیده
منابع مشابه
Cytokines and Signaling Molecules Predict Clinical Outcomes in Sepsis
INTRODUCTION Inflammatory response during sepsis is incompletely understood due to small sample sizes and variable timing of measurements following the onset of symptoms. The vasopressin in septic shock trial (VASST) compared the addition of vasopressin to norepinephrine alone in patients with septic shock. During this study plasma was collected and 39 cytokines measured in a 363 patients at bo...
متن کاملetiology and clinical outcomes of neonatal and pediatric sepsis
background sepsis can be defined as the body’s response to an infection. sepsis in children remains a significant cause of morbidity and mortality worldwide. objectives this study focuses on the etiological factors, risk factors, and clinical characteristics of sepsis in neonate and pediatric patients. patients and methods a prospective study was conducted over a six-month period in the pediatr...
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Sepsis is a constellation of clinical signs and symptoms resulting from excessive systemic host inflammatory response to infection. This inflammatory response is largely mediated by cytokines, which are released into the systemic circulation. Plasma concentrations of specific cytokines, TNF alpha, IL-1 beta, IL-6 and IL-8 are frequently elevated in human sepsis and cytokine concentrations corre...
متن کاملJaks, STATs, Cytokines, and Sepsis.
Sepsis remains a significant cause of morbidity and mortality in the intensive care unit (68), affecting more than 500,000 patients per year in the United States (39). The incidence is increasing despite the major advances in the development of antimicrobial agents and other supportive treatments (56). Septic patients often succumb to a systemic inflammatory response, of which multiple organ fa...
متن کاملEEG and clinical features of childhood absence predict clinical outcomes.
Commentary Childhood absence epilepsy (CAE) is a common pediatric epilepsy syndrome, accounting for approximately 10 to 17 percent of childhood epilepsy (1, 2). The EEG pattern in CAE is an approximate 3-Hz bilateral synchronous, symmetric spike and slow wave, with seizures often activated by hyperventila-tion (HV). Treatment of CAE is not optimal, with many children having incomplete seizure c...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0079207